![]() Once inside, the adenovirus escapes from the bubble and travels to the nucleus, the chamber where the cell’s DNA is stored.Ī dose of the Johnson & Johnson vaccine. ![]() The cell engulfs the virus in a bubble and pulls it inside. As a result, the Johnson & Johnson vaccine can be refrigerated for up to three months at 36–46☏ (2–8☌).Īfter the vaccine is injected into a person’s arm, the adenoviruses bump into cells and latch onto proteins on their surface. DNA is not as fragile as RNA, and the adenovirus’s tough protein coat helps protect the genetic material inside. Some other coronavirus vaccines are also based on adenoviruses, such as the one developed by the University of Oxford and AstraZeneca using a chimpanzee adenovirus.Īdenovirus-based vaccines for Covid-19 are more rugged than mRNA vaccines from Pfizer and Moderna. The company is also running trials on adenovirus-based vaccines for other diseases, including H.I.V. In July, the first one was approved for general use - a vaccine for Ebola, also made by Johnson & Johnson.
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